Halo nevus

Halo nevus

Classification and external resources
Specialty	dermatology
ICD-10	I78.1, D22 (ILDS D22.L34)
ICD-9-CM	448.1, 216.0-216.9, 757.32
ICD-O	8723/0
OMIM	234300
DiseasesDB	8333
eMedicine	derm/174
MeSH	D009508

Halo nevus (also known as "Leukoderma acquisitum centrifugum," "Perinevoid vitiligo," and "Sutton nevus"^[1]^:689) is a mole that is surrounded by a depigmented ring or 'halo'.

Background

Halo nevi are also known as Sutton's nevi, or leukoderma acquisitum centrifugum. Halo nevi are named such because they are a mole (nevi) that is surrounded by an area of depigmentation that resembles a halo.

Halo nevi are associated with vitiligo. Sometimes the pale (hypopigmented) areas will spontaneous regress, and pigment returns.

Causes

The formation of a halo surrounding a nevi is believed to occur when certain white blood cells called CD8+ T lymphocytes destroy the pigment-producing cells of the skin (melanocytes).^[2] The cause for the attack is unknown.^[3]

Predilection

Photograph of a halo nevus on a face

Halo nevi are estimated to be present in approximately 1% of the general population, and are found to be more prevalent in people with vitiligo, malignant melanoma,^[3] or Turner syndrome.^[4] All races and sexes are equally susceptible to this disease, although a familial tendency has been reported. The average age of onset is in a person's teenage years.

Treatment

As halo nevi are only of cosmetic significance, no treatment is required,^[5] and patients will be asymptomatic. Although halo nevi are harmless, it is important to monitor the lesion on regular basis.^[6] Watch out for any changes in appearance of existing or new halo nevi. If there is any change in appearance or is associated with pain, itch, and infection, a doctor should be consulted immediately to exclude the possibility of melanoma.

References

↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
↑ Mundinger, Gerhard S. (January 16, 2014). "Halo Phenomenon". New England Journal of Medicine. 370 (3): 262–262. doi:10.1056/NEJMicm1306230.
1 2 "Halo Nevus - skinsite.com". Retrieved August 4, 2008.
↑ Halo Nevis at eMedicine
↑ "CareFair.com - Halo Nevis". Retrieved August 4, 2008.
↑ "DermaTalk - Halo Nevus".

External links

Halo Nevus About.com article
thenevus.com - Halo Nevus Proves Halos Are Not Just For Angels

Tumors: Skin neoplasm, nevi and melanomas (C43/D22, 172/216, ICD-O 8720-8799)

Melanoma

Nevus/
melanocytic nevus

Cardiovascular disease (vessels) (I70–I99, 440–456)

Arteries, arterioles
and capillaries

Inflammation

Peripheral artery disease

Arteriosclerosis	Atherosclerosis Foam cell Fatty streak Atheroma Intermittent claudication Critical limb ischemia Monckeberg's arteriosclerosis Arteriolosclerosis Hyaline Hyperplastic Cholesterol LDL Oxycholesterol Trans fat

Stenosis	Carotid artery stenosis Renal artery stenosis

Other	Aortoiliac occlusive disease Degos disease Erythromelalgia Fibromuscular dysplasia Raynaud's phenomenon

Aneurysm / dissection /
pseudoaneurysm

Vascular malformation

Vascular nevus

Veins

Inflammation	Phlebitis

Venous thrombosis / Thrombophlebitis	primarily lower limb Deep vein thrombosis abdomen Hepatic veno-occlusive disease Budd–Chiari syndrome May–Thurner syndrome Portal vein thrombosis Renal vein thrombosis upper limb / torso Mondor's disease Paget–Schroetter disease head Cerebral venous sinus thrombosis Post-thrombotic syndrome

Varicose veins	Gastric varices Portacaval anastomosis Caput medusae Esophageal varices Hemorrhoid Varicocele

Other	Chronic venous insufficiency Chronic cerebrospinal venous insufficiency Superior vena cava syndrome Inferior vena cava syndrome Venous ulcer

Arteries or veins

Blood pressure

Hypertension	Hypertensive heart disease Hypertensive emergency Hypertensive nephropathy Essential hypertension Secondary hypertension Renovascular hypertension Benign hypertension Pulmonary hypertension Systolic hypertension White coat hypertension

Hypotension	Orthostatic hypotension

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