Girinimbine
 | |
| Names | |
|---|---|
| IUPAC name
3,3,5-Trimethyl-11H-pyrano[3,2-a]carbazole | |
| Other names
Girinimbin | |
| Identifiers | |
| 23095-44-5 | |
| 3D model (Jmol) | Interactive image |
| ChEBI | CHEBI:69926 |
| ChemSpider | 87534 |
| PubChem | 96943 |
| |
| |
| Properties | |
| C18H17NO | |
| Molar mass | 263.34 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Girinimbine is a carbazole alkaloid isolated from the curry tree (Murraya koenigii) along with the related alkaloids mahanimbine,[1] koenimbine,[2] isomahanine,[3] mahanine,[4] and others.[5]
A 2011 study of girinimbine found that it inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells in vitro.[6]
References
- ↑ CID 167963 from PubChem
- ↑ Metabocard for Koenimbine
- ↑ Isomahanine
- ↑ Mahanine
- ↑ Jain, Vandana; et al. (2012). "Murraya Koenigii: An Updated Review" (PDF). International Journal of Ayurvedic and Herbal Medicine. 2 (2): 607:627. ISSN 2249-5746. Retrieved 2014-10-11.
- ↑ Syam, Suvitha; Abdul, Ahmad Bustamam; Sukari, Mohd. Aspollah; Mohan, Syam; Abdelwahab, Siddig Ibrahim; Wah, Tang Sook (2011). "The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest". Molecules. 16 (8): 7155–70. doi:10.3390/molecules16087155. PMID 21862957.
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