Furafylline

Furafylline
Identifiers

IUPAC name 3-(furan-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
CAS Number	80288-49-9^Y
PubChem (CID)	3433
UNII	C2087G0XX3^N
ChEMBL	CHEMBL372638^N
Chemical and physical data
Formula	C₁₂H₁₂N₄O₃
Molar mass	260.25 g/mol
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Furafylline is a methylxanthine derivative that was introduced in hope of being a long-acting replacement for theophylline in the treatment of asthma.^[1] It is an inhibitor of CYP1A2.^[1]

References

1 2 Sesardic, D.; Boobis, A. R.; Murray, B. P.; Murray, S.; Segura, J.; De La Torre, R.; Davies, D. S. (1990). "Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man". British Journal of Clinical Pharmacology. 29 (6): 651–663. doi:10.1111/j.1365-2125.1990.tb03686.x. PMC 1380167. PMID 2378786.

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