Eptazocine
 | |
 | |
| Clinical data | |
|---|---|
| Routes of administration | Oral |
| ATC code | None |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number |
72522-13-5 72150-17-5 (bromide) |
| PubChem (CID) | 3042090 |
| ChemSpider | 2305268 |
| UNII | 2208ZLI77S |
| ChEMBL | CHEMBL70566 |
| Chemical and physical data | |
| Formula | C15H21NO |
| Molar mass | 231.333 g/mol |
| 3D model (Jmol) | Interactive image |
| |
| |
Eptazocine (Sedapain) is an opioid analgesic which was introduced in Japan by Morishita in 1987.[1][2][3][4] It acts as a mixed κ-opioid receptor agonist and μ-opioid receptor antagonist.[4][5][6]
See also
References
- ↑ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 396. ISBN 978-3-88763-075-1. Retrieved 29 November 2011.
- ↑ American Chemical Society. Division of Medicinal Chemistry (1990). Annual Reports in Medicinal Chemistry. Academic Press. p. 381. ISBN 978-0-12-040525-1. Retrieved 29 November 2011.
- ↑ Nabeshima T, Matsuno K, Kamei H, Kameyama T (May 1985). "The interaction of eptazocine, a novel analgesic, with opioid receptors". Research Communications in Chemical Pathology and Pharmacology. 48 (2): 173–81. PMID 2992058.
- 1 2 Hiroshi Nagase; Silvia N. Calderon (21 January 2011). Chemistry of Opioids. Springer. p. 280. ISBN 978-3-642-18106-1. Retrieved 29 November 2011.
- ↑ Tamura T, Ogawa J, Taniguchi T, Waki I (January 1990). "[Preferential action of eptazocine, a novel analgesic, with opioid receptors in isolated guinea pig ileum and mouse vas deferens preparations]". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese). 95 (1): 41–6. doi:10.1254/fpj.95.1_41. PMID 2154395.
- ↑ Ian Morton; Ian K. M. Morton; Judith M. Hall (1999). Concise dictionary of pharmacological agents: properties and synonyms. Springer. p. 113. ISBN 978-0-7514-0499-9. Retrieved 29 November 2011.
This article is issued from Wikipedia - version of the 10/15/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.