Potassium gluconate

Potassium gluconate
Clinical data

AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a601072
ATC code	A12BA05 (WHO)
Identifiers
IUPAC name Potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
CAS Number	299-27-4^N
PubChem (CID)	16760467
ChemSpider	8931^Y
E number	E577 (acidity regulators, ...)
ECHA InfoCard	100.005.523
Chemical and physical data
Formula	C₆H₁₁KO₇
Molar mass	234.246 g/mol
3D model (Jmol)	Interactive image
Melting point	180 °C (356 °F) (decomposes)
SMILES [K+].[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI InChI=1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1^Y Key:HLCFGWHYROZGBI-JJKGCWMISA-M^Y
^NY (what is this?) (verify)

Potassium gluconate is the potassium salt of the conjugate base of gluconic acid. It is also referred to as 2,3,4,5,6-pentahydroxycaproic acid potassium salt, D-gluconic acid potassium salt, or potassium D-gluconate.^[1]

It contains 16.69% potassium by mass. Thus 5.99 g of potassium gluconate contains 1 g of potassium.

It has a density of 1.73 g/cm³.^[2]

Dietary uses

Potassium gluconate is used as a mineral supplement and sequestrant. It is sold over-the-counter as tablets or capsules providing up to 593 mg of potassium gluconate, thereby containing 99 mg or 2.53 mEq of elemental potassium. This is the permissible upper limit for each tablet or capsule of over-the-counter potassium supplements sold in the USA. Potassium gluconate is also sold over-the-counter as bulk powder.

Safety

Its oral median lethal dose (LD₅₀) in rats is 10.38 g/kg.^[3] This is not an indicator of a safe oral daily dose in rats or humans.

References

↑ "Product Name potassium gluconate". Sigma-Aldrich. Retrieved 2013-03-09.
↑ "Potassium gluconate". Wolfram Alpha. Retrieved 2013-04-21.
↑ "MSDS - P1847". Sigma-Aldrich. Retrieved 2013-04-21.

External links

Mineral supplements (A12)

Major

Calcium	β-hydroxy-β-methylbutyrate carbonate chloride +cholecalciferol citrate glubionate glucoheptonate gluconate^# glycerylphosphate hydroxyapatite lactate gluconate lactate pangamate phosphate

Magnesium	aspartate chloride citrate gluconate glycinate lactate levulinate malate orotate oxide pidolate sulfate taurate

Phosphorus	adenosine triphosphate disodium hydroxyapatite monosodium phosphate

Potassium	bicarbonate bitartrate chloride citrate gluconate

Sodium	chloride sulfate

Sulfur	L-cysteine L-cystine L-glutathione L-methionine methylsulfonylmethane N-acetyl-L-cysteine R-α-lipoic acid S-adenosyl methionine taurine

Trace

Copper	gluconate

Iodine	potassium iodide

Iron	(II) fumarate (II) sulfate

Selenium	selenate selenite

Zinc	acetate L-aspartate L-carnosine gluconate oxide proteinate sulfate

Ultratrace

Chromium	(III) picolinate (III) chloride

Fluorine	fluoride^# monofluorophosphate

Lithium	aspartate carbonate orotate

Vanadium	(IV) sulfate

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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