N-Nitrosodiethylamine

Not to be confused with N-Nitrosodimethylamine.
N-Nitrosodiethylamine
Names
IUPAC name
N-Ethyl-N-nitrosoethanamine
Other names
Diethylnitrosamine; DENA
Identifiers
55-18-5
3D model (Jmol) Interactive image
PubChem 5921
Properties
C4H10N2O
Molar mass 102.14 g·mol−1
Appearance Yellow liquid[1]
Density 0.95 g/mL[1]
Boiling point 177 °C (351 °F; 450 K)[1]
Related compounds
Related compounds
Diethylamine, N-Nitrosodimethylamine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

N-Nitrosodiethylamine is a carcinogenic and mutagenic[2] organic compound, classified as a nitrosamine. It is found in tobacco smoke.[3]

It is classified as a Group 2A carcinogen (probable human carcinogen) by the World Health Organization.[4]

References

  1. 1 2 3 "N-Nitrosodiethylamine". Sigma-Aldrich.
  2. Verna, L; Whysner, J; Williams, G. M. (1996). "N-nitrosodiethylamine mechanistic data and risk assessment: Bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation". Pharmacology & therapeutics. 71 (1–2): 57–81. PMID 8910949.
  3. Tricker, A. R.; Ditrich, C; Preussmann, R (1991). "N-nitroso compounds in cigarette tobacco and their occurrence in mainstream tobacco smoke". Carcinogenesis. 12 (2): 257–61. PMID 1995191.
  4. "List of Classifications, Volumes 1-115". IARC Monographs on the Evaluation of Risk to Humans. International Agency for Research on Cancer. February 22, 2016. Retrieved July 26, 2016.
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