Cystamine
Not to be confused with cysteamine.
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| Names | |
|---|---|
| IUPAC name
2,2'-Dithiobis(ethylamine) | |
| Other names
2,2'-Dithiobisethanamine 2-Aminoethyl disulfide Decarboxycystine | |
| Identifiers | |
51-85-4  | |
| 3D model (Jmol) | Interactive image |
| Abbreviations | AED |
| ChEBI | CHEBI:78757  |
| ChEMBL | ChEMBL61350 |
| ChemSpider | 2812 |
| ECHA InfoCard | 100.000.119 |
| PubChem | 2915 |
| UNII | R110LV8L02 |
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| Properties | |
| C4H12N2S2 | |
| Molar mass | 152.28 g/mol[1] |
| Appearance | Viscous oil |
| Boiling point | Decomposes |
| Miscible | |
| Solubility in Ethanol | Soluble |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Cystamine is an organic disulfide. It is formed when cystine is heated, the result of decarboxylation. Cystamine is an unstable liquid and is generally handled as the dihydrochloride salt, C4H12N2S2·2HCl, which is stable to 203-214 °C at which point it decomposes. Cystamine is toxic if swallowed or inhaled and potentially harmful by contact.
Uses
Cystamine dihydrochloride is a useful reagent to derivatize various polymer monoliths for hydrophilic interaction liquid chromatography, as a crosslinking agent in the development of polymer hydrogels, and as a functional group in nanoparticles developed for siRNA and DNA delivery.
It has also been studied as a potential radioprotective agent.[2]
References
- ↑ Merck Index, 12th Edition, 2846.
- ↑ Elks, J.; Ganellin, C. R. (1990). "Dictionary of Drugs". doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2087-7.
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