Coclaurine
 | |
| Names | |
|---|---|
| IUPAC name
(1S)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol | |
| Identifiers | |
| 486-39-5 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 141028 |
| PubChem | 160487 |
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| |
| Properties | |
| C17H19NO3 | |
| Molar mass | 285.34 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Coclaurine is a nicotinic acetylcholine receptor antagonist which has been isolated from a variety of plant sources including Nelumbo nucifera, Sarcopetalum harveyanum,[1] Ocotea duckei,[2] and others. It belongs to the class of tetrahydroisoquinoline alkaloids. Dimerization of coclaurine leads to the biscoclaurine alkaloids such as cepharanthine.
References
- ↑ Sowemimo BO, Beal JL, Doskotch RW, Svoboda GH (1972). "The isolation of stepharine and coclaurine from Sarcopetalum harveyanum". Lloydia. 35 (1): 90–91. PMID 5037484.
- ↑ I.G da Silva; J.M Barbosa-Filho; M.S da Silva; C.D.G de Lacerda; E.V.L da-Cunha (2002). "Coclaurine from Ocotea duckei". Biochemical Systematics and Ecology. 30 (9): 881–883. doi:10.1016/s0305-1978(02)00024-8.
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