Cinaciguat

Cinaciguat
Clinical data
Routes of
administration
intravenous (?)
ATC code none
Identifiers
CAS Number 329773-35-5 YesY
PubChem (CID) 9808022
IUPHAR/BPS 5168
ChemSpider 7983781 N
UNII 59K0Y58UAD YesY
Chemical and physical data
Formula C36H39NO5
Molar mass 565.697 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Cinaciguat (BAY 58-2667) is an experimental drug for the treatment of acute decompensated heart failure.

Mechanism of action

Cinaciguat activates the soluble guanylate cyclase (sGC) which is a receptor for nitric oxide. This increases biosynthesis of cyclic GMP, resulting in vasodilation.[1]

See also

References

  1. Schubert-Zsilavecz, M, Wurglics, M, Neue Arzneimittel 2009



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