BD-1047

BD-1047
Clinical data
ATC code none
Identifiers
CAS Number 138356-20-4 N
PubChem (CID) 188914
IUPHAR/BPS 6680
ChemSpider 164154 YesY
ChEMBL CHEMBL143360 YesY
Chemical and physical data
Formula C13H20Cl2N2
Molar mass 275.217 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

BD-1047 is a sigma receptor antagonist, selective for the σ1 subtype. It has effects in animal studies suggestive of antipsychotic activity and may also be useful in the treatment of neuropathic pain.[1][2]

References

  1. Skuza G, Rogóz Z (2006). "Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity". Pharmacological Reports : PR. 58 (5): 626–35. PMID 17085854.
  2. Roh DH, Kim HW, Yoon SY, Seo HS, Kwon YB, Kim KW, Han HJ, Beitz AJ, Na HS, Lee JH (November 2008). "Intrathecal injection of the sigma(1) receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain". Anesthesiology. 109 (5): 879–89. doi:10.1097/ALN.0b013e3181895a83. PMID 18946301.


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