Alprenolol

Alprenolol
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code C07AA01 (WHO)
Pharmacokinetic data
Protein binding 80% - 90%
Biological half-life 2-3 hours → 4-OH-alprenolol
Identifiers
CAS Number 13655-52-2 YesY
PubChem (CID) 2119
IUPHAR/BPS 563
DrugBank DB00866 YesY
ChemSpider 2035 YesY
UNII 877K5MQ27W YesY
KEGG D07156 YesY
ChEBI CHEBI:51211 YesY
ChEMBL CHEMBL266195 YesY
Chemical and physical data
Formula C15H23NO2
Molar mass 249.34 g/mol
3D model (Jmol) Interactive image
  (verify)

Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as 5-HT1A receptor antagonist, used in the treatment of angina pectoris.[1] It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.

References

  1. Hickie JB (August 1970). "Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial". Med. J. Aust. 2 (6): 268–72. PMID 4393977.
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