Al-Sanamayn District (Arabic: منطقة الصنمين) is a district (mantiqah) administratively belonging to Daraa Governorate, Syria. At the 2004 Census it had a population of 167,993. Its administrative centre is the city of Al-Sanamayn.
The district of Al-Sanamayn is divided into three sub-districts or Nāḥiyas (population according to 2004 official census):
- Al-Sanamayn Nahiyah (ناحية الصنمين): population 113,316.
- Al-Masmiyah Nahiyah (ناحية المسمية) :population 8,773.
- Ghabaghib Nahiyah (ناحية غباغب): population 45,793.