ATP11B

ATP11B
Identifiers
Aliases	ATP11B, ATPIF, ATPIR, ATPase phospholipid transporting 11B (putative)
External IDs	MGI: 1923545 HomoloGene: 32919 GeneCards: ATP11B
Gene ontology Molecular function • nucleotide binding • ion transmembrane transporter activity • metal ion binding • protein binding • phospholipid-translocating ATPase activity • hydrolase activity • ATP binding • magnesium ion binding Cellular component • integral component of membrane • recycling endosome • endosome • Golgi apparatus • membrane • plasma membrane • nuclear inner membrane • recycling endosome membrane • early endosome • endoplasmic reticulum Biological process • lipid transport • aminophospholipid transport • phospholipid transport • ion transport • ion transmembrane transport • phospholipid translocation • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23200	76295
Ensembl	ENSG00000058063	ENSMUSG00000037400
UniProt	Q9Y2G3	n/a
RefSeq (mRNA)	NM_014616	NM_029570
RefSeq (protein)	NP_055431.1	n/a
Location (UCSC)	Chr 3: 182.79 – 182.92 Mb	Chr 3: 35.75 – 35.86 Mb
PubMed search	[1]	[2]
Wikidata

Probable phospholipid-transporting ATPase IF is an enzyme that in humans is encoded by the ATP11B gene.^[3][4][5]

Function

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.^[5]

References

Further reading