ANAPC11

ANAPC11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases ANAPC11, APC11, Apc11p, HSPC214, anaphase promoting complex subunit 11
External IDs MGI: 1913406 HomoloGene: 41136 GeneCards: ANAPC11
Orthologs
Species Human Mouse
Entrez

51529

66156

Ensembl

ENSG00000141552

ENSMUSG00000025135

UniProt

Q9NYG5

Q9CPX9

RefSeq (mRNA)

NM_001038230
NM_025389

RefSeq (protein)

NP_001033319.1
NP_079665.1

Location (UCSC) Chr 17: 81.89 – 81.9 Mb Chr 11: 120.6 – 120.61 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene.[3][4]

Interactions

ANAPC11 has been shown to interact with ANAPC2[5][6] and CDC27.[3][7]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. 1 2 Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM (Sep 2000). "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex". Proc Natl Acad Sci U S A. 97 (16): 8973–8. doi:10.1073/pnas.97.16.8973. PMC 16806Freely accessible. PMID 10922056.
  4. "Entrez Gene: ANAPC11 APC11 anaphase promoting complex subunit 11 homolog (yeast)".
  5. Tang, Z; Li B; Bharadwaj R; Zhu H; Ozkan E; Hakala K; Deisenhofer J; Yu H (Dec 2001). "APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Mol. Biol. Cell. United States. 12 (12): 3839–51. doi:10.1091/mbc.12.12.3839. ISSN 1059-1524. PMC 60759Freely accessible. PMID 11739784.
  6. Ohta, T; Michel J J; Schottelius A J; Xiong Y (Apr 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol. Cell. UNITED STATES. 3 (4): 535–41. doi:10.1016/S1097-2765(00)80482-7. ISSN 1097-2765. PMID 10230407.
  7. Vodermaier, Hartmut C; Gieffers, Christian; Maurer-Stroh, Sebastian; Eisenhaber, Frank; Peters, Jan-Michael (Sep 2003). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Curr. Biol. England. 13 (17): 1459–68. doi:10.1016/S0960-9822(03)00581-5. ISSN 0960-9822. PMID 12956947.

Further reading

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