4-Hydroxymandelic acid

4-Hydroxymandelic acid
Chemical structure of 4-Hydroxymandelic acid
Names
Preferred IUPAC name
Hydroxy(4-hydroxyphenyl)acetic acid
Other names
2-Hydroxy-2-(4-hydroxyphenyl)acetic acid
4-Hydroxyphenylglycolic acid
p-Hydroxymandelic acid
4-Hydroxymandelate
Identifiers
1198-84-1 YesY
184901-84-6 (hydrate)
3D model (Jmol) Interactive image
2365374
ChemSpider 321 YesY
ECHA InfoCard 100.013.490
EC Number 214-839-7
PubChem 328
Properties
C8H8O4
Molar mass 168.15 g·mol−1
Appearance Light red powder
Melting point 89 °C (192 °F; 362 K)
Hazards
Safety data sheet MSDS at Sigma Aldrich
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

4-Hydroxymandelic acid is a chemical compound used to synthesize atenolol.[1] The compound typically occurs as a monohydrate (C8H8O4 • H2O at 186.16 g/mol).

Synthesis

4-Hydroxymandelic acid is obtained by the condensation reaction between phenol and glyoxylic acid.[1]

See also

References

  1. 1 2 Mattioda, Georges & Christidis, Yani (2000). "Glyoxylic Acid". Ullmann's Encyclopedia of Industrial Chemistry: pg. 2. doi:10.1002/14356007.a12_495. Retrieved 27 December 2013.
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