5-Androstenedione

5-Androstenedione
Clinical data
Routes of
administration
Oral
Identifiers
Synonyms Androst-5-ene-3,17-dione; Δ5-Androstenedione; NSC-12873
CAS Number 571-36-8 YesY
PubChem (CID) 160531
DrugBank DB01456
ChemSpider 141063
UNII HEE11L5C3G YesY
ChEBI CHEBI:83865
ChEMBL CHEMBL1743203
Chemical and physical data
Formula C19H26O2
Molar mass 286.415 g/mol
3D model (Jmol) Interactive image

5-Androstenedione is a prohormone of testosterone. The World Anti-Doping Agency prohibits its use in athletes. In the United States, it is a controlled substance.

5-Androstenedione is structurally similar to 4-androstenedione, with the exception of the position of a carbon-carbon double bond. 4-Androstenedione is naturally produced in the body by the adrenal glands and gonads. In addition to testosterone, it is also a precursor of estrone and estradiol.[1][2]

References

  1. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). "DrugBank 3.0: a comprehensive resource for omics research on drugs". Nucleic Acids Res. 39 (Database issue): D1035–41. doi:10.1093/nar/gkq1126. PMC 3013709Freely accessible. PMID 21059682.
  2. Wishart, David S.; Knox, Craig; Guo, An Chi; Cheng, Dean; Shrivastava, Savita; Tzur, Dan; Gautam, Bijaya; Hassanali, Murtaza (2008). "DrugBank: a knowledgebase for drugs, drug actions and drug targets". Nucleic Acids Research. 36 (Database issue): D901–6. doi:10.1093/nar/gkm958. PMC 2238889Freely accessible. PMID 18048412.

External links



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